[HTML][HTML] Oxygen homeostasis and cardiovascular disease: A role for HIF?

X Li, Q Zhang, MI Nasser, L Xu, X Zhang, P Zhu… - Biomedicine & …, 2020 - Elsevier
… -1 can regulate the adaptive cellular responses to hypoxia by … of pulmonary arterial endothelial
cells causes vascular … reduced intimal proliferation and down-regulation of E-selectin and …

Mechanisms underlying the influence of oestrogen on cardiovascular physiology in women

S Novella, D Pérez‐Cremades… - The Journal of …, 2019 - Wiley Online Library
… in cerebral blood vessels from ovariectomized rats, where … miR-22 down-regulation increases
the expression of its … of ERβ/ERα in both vascular endothelium and smooth muscle in aged …

Endothelin and the heart in health and diseases

T Miyauchi, S Sakai - Peptides, 2019 - Elsevier
… Although vascular endothelial cells are the major source of ET-… that agonist-induced receptor
down-regulation may exist in the … renal endothelin receptor density and urinary endothelin

Non-coding RNA regulation of endothelial and macrophage functions during atherosclerosis

B Aryal, Y Suárez - Vascular pharmacology, 2019 - Elsevier
damage, hypoxia and cytokine inflammatory stimulation. In response to inflammatory stimuli
mainly mediated by NF-kB activation, the vascular endothelium … inflammatory ligand serum …

Hypoxia-inducible factors not only regulate but also are myeloid-cell treatment targets

L Kling, A Schreiber, KU Eckardt… - Journal of leukocyte …, 2021 - academic.oup.com
… B scavenger receptor CD36 and its ligand thrombospondin-1 … , combined PHD down-regulation
and up-regulation of HIF … Subsequently, endothelin receptor stimulation activated …

CircRNA–miRNA interactions in atherogenesis

KL Tong, KE Tan, YY Lim, XY Tien, PF Wong - Molecular and cellular …, 2022 - Springer
… One of the most common mechanism of action of circRNAs … The vascular endothelium acts
as a barrier between … species (ROS), endothelin-1 (ET-1), and cell adhesion molecule (CAM) …

[HTML][HTML] The dual roles of autophagy and the GPCRs-mediating autophagy signaling pathway after cerebral ischemic stroke

W Hou, Y Hao, L Sun, Y Zhao, X Zheng, L Song - Molecular Brain, 2022 - Springer
… of a variety of hypoxia-responsive genes, such as vascular endothelial growth factor, … infarct
volume in rats exposed to transient focal cerebral ischemia [70]. Down-regulation of beclin-1 …

Potential regulation mechanisms of P-gp in the blood-brain barrier in hypoxia

Y Ding, R Wang, J Zhang, A Zhao, H Lu… - Current …, 2019 - ingentaconnect.com
… -1-phosphate receptor 1 (S1P), vascular endothelial growth … may play an important role in
the down-regulation of P-gp activity. … differences in cell signaling and ligand specificity, rat and …

[HTML][HTML] Effects of thyroid hormone on tissue hypoxia: relevance to sepsis therapy

AI Lourbopoulos, IS Mourouzis, AG Trikas… - Journal of Clinical …, 2021 - mdpi.com
… vivo and in vitro via vascular endothelial growth factor A (VEGF… percentage of injured
mitochondria, and down-regulation of … Ligand-bound TRα on macrophages protected the kidney, …

Role of liver sinusoidal endothelial cells in liver diseases

J Gracia-Sancho, E Caparrós… - Nature reviews …, 2021 - nature.com
… and other vascular endothelial cells. In the 1970s, the … -associated molecular patterns (DAMPs)
induced by cellular hypoxia. … used bosentan, an antagonist of endothelin receptors, and …